C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) C07K 14/705 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2425872
The present invention relates to flea GABA receptor subunit nucleic acid molecules; to flea GABA receptor subunit proteins encoded by such nucleic acid molecules; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and inhibitory compounds, particularly those that specifically inhibit flea GABA receptor subunit activity, as well as the use of such therapeutic compositions to treat animals.
L'invention concerne des molécules d'acide nucléique de sous-unité de récepteur GABA de puce, des protéines de sous-unité de récepteur GABA de puce codées par ces molécules d'acide nucléique, des anticorps dirigés contre ces protéines, et des composés inhibant l'activité de ces protéines. Cette invention concerne également des procédés d'obtention de ces protéines, molécules d'acide nucléique, anticorps, et composés inhibiteurs. Elle concerne enfin des compositions thérapeutiques comprenant ces protéines, molécules d'acide nucléique, anticorps et composés inhibiteurs, notamment ceux qui inhibent de manière spécifique l'activité de la sous-unité du récepteur GABA de puce, ainsi que l'utilisation de ces compositions thérapeutiques dans le traitement d'animaux.
Brandt Kevin S.
Wisnewski Nancy
Heska Corporation
Parlee Mclaws Llp
LandOfFree
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