C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2425486
The present invention relates to flea peritrophin proteins; to flea peritrophin nucleic acid molecules, including those that encode such flea peritrophin proteins; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain and use such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit flea peritrophin activity, as weell as the use of such therapeutic compositions to treat animals.
L'invention concerne des protéines de péritrophine des puces et des molécules d'acide nucléique de péritrophine de puce, y compris les molécules d'acide nucléique codant pour de telles protéines de péritrophine, des anticorps dirigés contre ces protéines et des composés inhibant l'activité de ces protéines. L'invention concerne également des procédés permettant d'obtenir et d'utiliser ces protéines, molécules d'acide nucléique, anticorps et composés inhibiteurs. L'invention concerne en outre des compositions thérapeutiques comprenant de tels composés inhibiteurs, en particulier des composés qui inhibent de manière spécifique l'activité de la péritrophine de puce, ainsi que l'utilisation de ces compositions thérapeutiques pour le traitement d'animaux.
Gaines Patrick J.
Wisnewski Nancy
Heska Corporation
Johnson Ernest Peter
LandOfFree
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