Flj10607 as modifier of the axin pathway and methods of use

Details Flj10607 as modifier of the axin pathway and methods of use Flj10607 as modifier of the axin pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2506958

Human FLJ10607 genes are identified as modulators of the Axin pathway, and thus are therapeutic targets for disorders associated with defective Axin function. Methods for identifying modulators of Axin, comprising screening for agents that modulate the activity of FLJ10607 are provided.

Les gènes FLJ10607 humains sont identifiés en tant que modulateurs de la voie de l'axine; de ce fait, ces gènes représentent des cibles thérapeutiques pour des troubles associés à la fonction défectueuse de l'axine. L'invention concerne des procédés permettant d'identifier des modulateurs de l'axine, lesquels procédés consistent à cribler des agents qui modulent l'activité de FLJ10607.

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