Flj20647s as modifiers of the p21 pathway and methods of use

Details Flj20647s as modifiers of the p21 pathway and methods of use Flj20647s as modifiers of the p21 pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/00 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2497793

Human FLJ20647 genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of FLJ20647 are provided.

L'invention concerne des gènes humains FL20647 identifiés en tant que modulateurs de la voie p21 et les cibles thérapeutiques pour des troubles sont associées à un dysfonctionnement de la p21. L'invention concerne également de procédés d'identification de modulateurs de la p21, comprenant le criblage d'agents qui modulent l'activité de FLJ20647.

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