G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 21/85 (2006.01) G01N 11/04 (2006.01) G01N 15/14 (2006.01) G01N 21/05 (2006.01) G01N 33/49 (2006.01) G06F 15/70 (1990.01)
Patent
CA 2129886
Abstract of the Disclosure This invention relates to a flow cell device for the monitoring of cell suspension under flow. The device is particularly useful for monitoring red blood cells and their dynamic organization under flow conditions, as well as their shape and deformability, using small samples of suspensions, with a safe and cost effective procedure. The device is comprised of a set of plates including a rigid transparent base having an inlet and an outlet, a flow channel plate having a central hole of variable dimension defining the flow channel, a transparent plate over the flow channel plate, and a rigid cover with a hole enabling a microscope objective to approach the flow channel. The plates can be attached to each other firmly by using bond screws or other methods. Alternatively, the flow channel plate could be manufactured as an integral part with either the base or the transparent plate. Syringes or other suitable means are used to supply and receive the suspension sample. The device can be connected via the microscope to a video camera, a computer and an image monitor.
Chen Shuqi
Gavish Benjamin
Yedgar Saul
Shapiro Cohen
Yissum Research Development Company Of The Hebrew University Of
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