Flow resistance modulated aerosolized active agent delivery

A - Human Necessities – 61 – M

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A61M 15/00 (2006.01)

Patent

CA 2346791

The present invention is directed to methods and devices for delivering an active agent formulation to the lung of a human patient. The active agent formulation may be in dry powder form, it may be nebulized, or it may be in admixture with a propellant. The active agent formulation is delivered to a patient at a low inspiratory flow rate for an initial period of time to increase bioavailability of the active agent.

L'invention concerne des méthodes et des dispositifs, permettant d'administrer une formulation d'agent actif dans les poumons d'un patient. Cette formulation d'agent actif peut se présenter sous forme de poudre, peut être nébulisée, ou peut être associée dans un mélange à un agent de propulsion. La formulation d'agent actif est administrée à un patient selon un débit inspiratoire faible pendant une durée initiale, afin d'augmenter la biodisponibilité de l'agent actif.

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