C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07H 21/04 (2006.01) C07K 14/71 (2006.01) C07K 16/40 (2006.01) C12N 5/20 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2192235
Anti-FLT4 antibodies, especially monoclonal anti-FLT4 antibodies, which are useful as a specific marker for endothelial cells of lymphatic vessels and HEVs, as a diagnostic tool for detecting changes in lymphatic tissue, especially in lymphatic vessels and HEVs in disease states, such as lymphangioma, metastatic lymph nodes and inflammatory, infectious and immunological disease.
L'invention concerne des anticorps anti-FLT4, en particulier des anticorps monoclonaux anti-FLT4 qui sont utiles en tant que marqueurs spécifiques des cellules endothéliales des vaisseaux lymphatiques et des veinules riches en cellules endothéliales, et comme agents de diagnostic pour détecter les changements dans le tissu lymphatique, en particulier dans les vaisseaux lymphatiques et les veinules riches en cellules endothéliales, par exemple l'apparition de lymphangiomes, de métastases des ganglions lymphatiques et de diverses autres maladies inflammatoires, infectieuses et immunologiques.
Alitalo Kari
Kaipainen Arja
Karnani Paivi
Korhonen Jaana
Matikainen Marja-Terttu
Alitalo Kari
Kaipainen Arja
Karnani Paivi
Korhonen Jaana
Matikainen Marja-Terttu
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