Fluid resuscitation

Details Fluid resuscitation Fluid resuscitation

A - Human Necessities

61

K

A61K 31/16 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2084073

ABSTRACT The invention relates to fluid resuscitation of the human or animal body by administration of deferoxamine (DFO) and a water- soluble biopolymer. The DFO and the biopolymer are preferably bonded toghether. The biopolymer may be a polysaccharide or a protein. The DFO and the biopolymer are preferably formulated as an aqueous solution suitable for oral administration. The fluid resuscitation may be effected for ameliorating systemic oxidant injury occuring during ischemia and subsequent reperfusion. The fluid resuscitation may be indicated in treatment of burn injury, lung injury caused by inhalation of hot and/or toxic substances, such as smoke derived from combusion, hemorrhagic shock and other types of trauma.

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