Fluidized intestinal submucosa and its use as an injectable...

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/38 (2006.01) A61F 2/28 (2006.01) A61L 27/00 (2006.01) A61L 27/36 (2006.01) A61F 2/02 (2006.01) A61F 2/30 (2006.01)

Patent

CA 2149324

A fluidized, injectable tissue graft composition is described. The composition comprises comminuted intestinal submucosa or protease-digested intestinal submucosa. Methods for the preparation and use of injectable tissue graft compositions are described. In preferred embodiments the tissue graft material is prepared from the intestinal submucosa comprising the tunics submucosa and basilar portions of the tunics mucosa of a segment of intestinal tissue of a warm-blooded vertebrate: Effective amounts of the fiuidized graft compositions can be injected to promote repair tissue defects by inducing formation of endogenous tissues.

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