Fluidized magaldrate suspension

Details Fluidized magaldrate suspension Fluidized magaldrate suspension

A - Human Necessities

61

K

167/124

A61K 33/08 (2006.01) A61K 9/14 (2006.01)

Patent

CA 1252045

ABSTRACT An aqueous antacid composition of magaldrate gel and a process for preparing same are described by the invention. The composition is prepared from and contains precipitated and undried magaldrate gel and a fluidizing of a first and second fluidizer. On fluidizer is provided by an aluminum hydroxide gel having colloidal properties and the second by a pharmaceutically acceptable citrate ion source including citric acid. The process and composition are characterized in providing a fluid, resuspendible, pharmaceutically elegant suspension possessing high antacid capacity and stability at even elevated magaldrate concentrations in addition to the ability to fluidize stiff, paste-like magaldrate gel cakes.

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