C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/48 (2006.01) A61K 31/4168 (2006.01) A61K 31/4184 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01) C07C 279/12 (2006.01) C07D 235/30 (2006.01)
Patent
CA 2380981
The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, m and n have the meaning given in Claim 1, and to their physiologically acceptable salts and solvates, which can be used as integrin inhibitors, especially for the prophylaxis and treatment of blood circulation disorders, thrombosis, myocardial infarction, coronary disorders, arteriosclerosis, osteoporosis, pathological processes which are maintained or propagated through angiogenesis, as well as in tumour therapy.
Composés de formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, m et n possèdent la signification figurant dans la revendication 1, ainsi que leurs sels et solvates physiologiquement acceptables, qui peuvent être utilisés comme inhibiteurs d'intégrine, en particulier pour la prophylaxie et le traitement de troubles de la circulation, de la thrombose, de l'infarctus du myocarde, des coronaropathies, de l'artériosclérose, de l'ostéoporose, de processus pathologiques qui sont entretenus ou propagés par l'angiogenèse, ainsi que dans la thérapie des tumeurs.
Goodman Simon
Stahle Wolfgang
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
LandOfFree
Fluorene derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fluorene derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorene derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1941490