Fluorescence-based methods for measuring enzyme activity

Details Fluorescence-based methods for measuring enzyme activity Fluorescence-based methods for measuring enzyme activity

C - Chemistry, Metallurgy

12

Q

C12Q 1/34 (2006.01) C12Q 1/25 (2006.01) C12Q 1/37 (2006.01) C12Q 1/44 (2006.01) C12Q 1/48 (2006.01) G01N 33/50 (2006.01) G01N 33/542 (2006.01) G01N 33/573 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2484467

The invention relates to fluorescence methods for measuring enzyme activity, in particular enzyme cleaving and joining activities. The invention also relates to fluorogenic substrates which are useful for measuring enzyme activity and as in vitro andin vivo imaging probes.

L'invention concerne des méthodes de fluorescence pour mesurer l'activité enzymatique, en particulier les activités de clivage et d'assemblage enzymatiques. L'invention concerne également des substrats fluorogènes lesquels sont utiles pour mesurer l'activité enzymatique telle que dans des sondes d'imagerie in vitro et in vivo.

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