G - Physics – 01 – N
Patent
G - Physics
01
N
167/43
G01N 33/533 (2006.01) G01N 33/94 (2006.01)
Patent
CA 1297001
ABSTRACT This disclosure related to a method and reagents for determining amphetamine and methamphetamine in a biological fluid such as urine. In particular, this disclosure relates to a fluorescence polarization immunoassay procedure for determining the presence of amphetamine and methamphetamine in a single assay and to a novel class of tracer compounds employed as reagents in such procedures. The procedure described includes pretreatment of the biological sample to eliminate cross-reactants such as .beta.-hydroxyphenethylamine by preincubating the sample solely with an aqueous periodate solution having a pH from about 4.0 to about 7.5 without adjustment to an alkaline pH.
557791
Brynes Paul Jeffrey
Martinus Janis Allison
Molina Cynthia Martha
Smith Catherine M.
Vaughan Kenward Shaw
Abbott Laboratories
Goudreau Gage Dubuc
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