C - Chemistry – Metallurgy – 09 – B
Patent
C - Chemistry, Metallurgy
09
B
C09B 23/02 (2006.01) C09B 57/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2178308
The present invention provides low molecular weight fluorescent labelling complexes with large wavelength shifts between absorption of one dye in the complex and emission from another dye in the complex. These complexes can be used, for example, for multiparameter fluorescence cell analysis using a single excitation wavelength. The low molecular weight of the complex permits materials labelled with the complex to penetrate cell structures for use as probes. The labelling complexes are synthesised by covalently attaching through linkers to form donor-acceptor complexes. Resonance energy transfer from an excited donor to fluorescent acceptor provides wavelength shifts up to 300nm. The fluorescent labelling complexes preferably contain reactive groups for the labelling of functional groups on target compounds, such as derivatised oxy and deoxy polynucleic acids, antibodies, enzymes, lipids, carbohydrates, proteins and other materials. The complexes may contain functional groups permitting covalent reaction with materials containing reactive groups.
Mujumdar Ratnakar B.
Mujumdar Swati R.
Waggoner Alan S.
Carnegie Mellon University
Mujumdar Ratnakar B.
Mujumdar Swati R.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Waggoner Alan S.
LandOfFree
Fluorescent labeling complexes with large stokes' shifts... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fluorescent labeling complexes with large stokes' shifts..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescent labeling complexes with large stokes' shifts... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1645493