C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C09K 11/06 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2113106
The invention relates to microparticles incorporating a series of two or more fluorescent dyes having overlapping excitation and emission spectra allowing efficient energy transfer from the excitation wavelength of the first dye in the series, transfer through the dyes in the series and re-emitted as an optical signal at the emission wavelength of last dye in the series, resulting in a desired effective Stokes shift which is controlled through selection of appropriate dyes.
L'invention se rapporte à des microparticules comprenant une série d'au moins deux colorants fluorescents présentant des spectres d'excitation et d'émission qui se chevauchent et permettent un transfert d'énergie efficace à partir de la longueur d'onde d'excitation du premier colorant de la série, l'énergie étant transférée à travers les colorants de la série et réémise sous forme d'un signal optique à la longueur d'onde d'émission du dernier colorant de la série, ce qui permet d'obtenir un décalage de Stokes requis efficace, qui est régulé au moyen de la sélection de colorants appropriés.
Brinkley John M.
Haugland Richard P.
Singer Victoria L.
Mbm Intellectual Property Law Llp
Molecular Probes Inc.
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