Fluorescent polarization immunoassay utilizing substituted...

Details Fluorescent polarization immunoassay utilizing substituted... Fluorescent polarization immunoassay utilizing substituted...

C - Chemistry, Metallurgy

07

D

260/255, 167/43,

C07D 311/82 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 473/08 (2006.01) C07J 19/00 (2006.01) C07J 41/00 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)

Patent

CA 1178269

A B S T R A C T This disclosure relates to a method and roagents for determining ligands in biological fluids such as serum, plasma, spinal fluid, amniotic fluid and urine. In particular, this disclosure relates to a fluorescence polarization immunoassy procedure and to a novel class of tracer compounds employed as reagents in such procedures. The procedure disclosed combines the specificity of an immunoassay with the speed and convience of fluorescence polarization techniques to provide a means for determining the amount of a specific ligand present in a sample.

396311

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