G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/58 (2006.01) C07K 17/08 (2006.01) C08F 8/00 (2006.01) C08G 69/48 (2006.01) G01N 33/53 (2006.01) G01N 33/533 (2006.01) C08B 37/16 (2006.01)
Patent
CA 2172999
The instant invention provides a highly fluorescent conjugate which is useful in specific binding assays, and which comprises a specific binding member bound to a fluorescent polymer. The fluorescent polymer comprises a backbone polymer having multiple signal generating groups immobilized thereon and, optionally, cyclodextrin moieties in association with the polymer. Also provided is a novel process for creating 6-cyclodextrin monoaldehyde.
L'invention concerne un conjugué extrêmement fluorescent présentant une efficacité dans des méthodes spécifiques d'immunodétection et comprenant un élément liant spécifique fixé à un polymère fluorescent. Le polymère fluorescent comprend un polymère squelette, sur lequel sont immobilisés des groupes multiples générateurs de signaux et, éventuellement, des fractions de cyclodextrine associées au polymère. L'invention concerne également un nouveau procédé de préparation de monoaldéhyde de 6-cyclodextrine.
Bieniarz Christopher
Huff Jeffrey Bruce
Abbott Laboratories
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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