Fluorescent probes for dna detection by hybridization with...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) G01N 33/58 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2542768

Minor groove binder-oligonucleotide probes are provided along with methods for their use wherein the probes have an attached fluorophore which, in an unhybridized form exhibits very low background signal.

L'invention concerne des sondes d'oligonucléotides de liants à rainure mineure, ainsi que leurs méthodes d'utilisation, lesdites sondes étant attachées à du fluorophore qui, à l'état non hybridé, présente un signal de fond très faible.

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