Fluorinated 2-nitroimidazole analogs for detecting hypoxic...

C - Chemistry – Metallurgy – 07 – D

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C07D 233/91 (2006.01) A61K 49/06 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2196900

Novel agents useful for detecting hypoxic tumor cells are provided. The compounds have structural formula (I), wherein R1 and R2 are as defined herein. Methods of using the compounds to detect hypoxic tumor cells are also provided, as are pharmaceutical compositions formulated with the novel compounds.

Nouveaux composés de détection des cellules hypoxyques de tumeurs, de formule (I), où R<1> et R<2> sont définis ici, leurs méthodes d'utilisation en vue de la détection desdites cellules, et préparations pharmaceutiques les contenant.

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