Fluorinated bile acid derivatives, processes for the...

Details Fluorinated bile acid derivatives, processes for the... Fluorinated bile acid derivatives, processes for the...

C - Chemistry, Metallurgy

07

J

167/195, 260/62

C07J 9/00 (2006.01) A61K 31/575 (2006.01) C07J 51/00 (2006.01)

Patent

CA 2014545

A compounds of general formula I Image wherein R1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in or B configuration, are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6 -hydroxy-7-keto-derivatives.

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