Fluorinated cyclobutyl purines and pyrimidines

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 473/00 (2006.01) A61K 31/505 (2006.01) A61K 31/675 (2006.01) C07C 43/178 (2006.01) C07C 43/315 (2006.01) C07C 45/51 (2006.01) C07C 49/753 (2006.01) C07C 62/08 (2006.01) C07C 69/757 (2006.01) C07C 309/30 (2006.01) C07C 309/73 (2006.01) C07D 239/46 (2006.01) C07D 303/08 (2006.01) C07D 303/48 (2006.01) C07F 7/18 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2088196

GY24a ABSTRACT Fluorinated Cyclobutyl Purines And Pyrimidines Antiviral activity is exhibited by compounds having the formula Image or a pharmaceutically acceptable salt thereof wherein R1 is a purinyl, substituted purinyl, pyrimidinyl, or substituted pyrimidinyl, R6 is -OH, -CH2OH-, -OPO3H2, -CH2-O-PO3H2, -O-?-R3, or -CH2-O-?-R3 , and R7 is hydrogen, -PO3H2, or -?-R3.

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