Fluorinated derivatives of deferiprone

Details Fluorinated derivatives of deferiprone Fluorinated derivatives of deferiprone

C - Chemistry, Metallurgy

07

D

C07D 213/69 (2006.01) A61K 31/351 (2006.01) A61K 31/4412 (2006.01) A61P 25/28 (2006.01) A61P 39/04 (2006.01) C07D 309/40 (2006.01)

Patent

CA 2627529

The present invention relates to novel derivatives of deferiprone. In particular, the present invention relates to fluorinated derivatives of deferiprone or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, processes for the manufacture thereof and their use in the treatment of neurodegenerative diseases caused by the presence of free iron or iron accumulation in neural tissues and in diseases wherein excess iron must be removed or redistributed.

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