Fluorinated diaminoalkene derivatives

Details Fluorinated diaminoalkene derivatives Fluorinated diaminoalkene derivatives

C - Chemistry, Metallurgy

07

C

260/520, 260/485

C07C 43/17 (2006.01) A61K 31/15 (2006.01) C07D 209/48 (2006.01)

Patent

CA 1204770

ABSTRACT FLUORINATED DIAMINOPENTENE DERIVATIVES Novel fluorinated alkenylene diamine derivatives are inhibitors of ornithine decarboxylase enzyme and have the following general Formula I:- Formula I Image wherein:- Rc represents hydrogen or -COR5, where R5 is as defined below; R1 represents hydrogen or C1-C6 alkyl; one of R2 and R3 represents hydrogen and the other represents C1-C6 alkyl; R5 represents hydroxy or C1-C8 alkoxy; m and n independently represent 0 or 1 but m + n = 0 or 1; p represents 1 or 2.

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