C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/34 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) C07D 239/46 (2006.01) C07D 239/52 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2494824
Disclosed are compounds of formula (I) wherein R1, R2, W and X of formula (I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
L'invention concerne des composés de formule (I), dans lesquels R¿1?, R¿2?, W et X de formule (I) sont tels que définis dans la description. Ces composés inhibent la production de cytokines impliquant des processus inflammatoires et sont donc utiles dans le traitement de maladies et d'états pathologiques impliquant une inflammation telle qu'une maladie inflammatoire chronique. L'invention concerne également des procédés de préparation de ces composés et des compositions pharmaceutiques comportant ces composés.
Cirillo Pier Francesco
Hammach Abdelhakim
Kamhi Victor
Moss Neil
Pargellis Christopher
Boehringer Ingelheim Pharmaceuticals Inc.
Fetherstonhaugh & Co.
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