C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 401/00 (2006.01) A61K 31/59 (2006.01)
Patent
CA 2141652
This invention is for 1.alpha.-fluoro-25-hydroxy-16-ene-23-yne- cholecalciferol, which can be further characterized by the formula: Image and which is useful as an agent for the treatment of sebaceous gland diseases such as acne and sebhorreic dermatitis. It can be prepared by removing the silyl protecting groups from a corresponding compound with silyl protected hydroxy groups.
Doran Thomas I.
Shiuey Shian-Jan
Uskokovic Milan Radoje
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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