Fluorination of aromatic ring systems

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 213/08 (2006.01) C07C 43/247 (2006.01) C07C 219/18 (2006.01) C07D 213/06 (2006.01) C07D 233/06 (2006.01) C07D 277/22 (2006.01)

Patent

CA 2741967

This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.

La présente invention concerne des réactifs et des procédés utiles dans la synthèse de fluorures daryle, par exemple, dans la préparation de radiotraceurs marqués avec 18F. Les réactifs et procédés présentement décrits peuvent être utilisés pour accéder à une large gamme de composés, comprenant des composés aromatiques, des composés hétéroaromatiques, des acides aminés, des nucléotides et des composés synthétiques.

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