Fluorine and phosphorous-containing amphiphilic molecules...

C - Chemistry – Metallurgy – 07 – F

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C07F 9/6533 (2006.01) A61K 9/00 (2006.01) A61K 9/127 (2006.01) A61K 47/24 (2006.01) A61K 49/00 (2006.01) C07F 9/09 (2006.01) C07F 9/10 (2006.01)

Patent

CA 2059288

Compounds of general formula (I) or (II) are useful as surfactants in the preparation of fluorocarbon emulsions, which can be used as oxygen-carrying blood substitutes, and for many other therapeutic and diagnostic applications. They are further useful in liposomal formulations which are themselves therapeutic agents or provide a vehicle for such agents.

Les composés des formules générales (I) ou (II) sont utiles en tant que tensio-actifs dans la préparation d'émulsions de fluorocarbone, pouvant servir de substituants du sang transportant l'oxygène, ainsi que dans beaucoup d'autres applications thérapeutiques et diagnostiques. Ils sont également utiles dans des formulations liposomiques, lesquelles constituent des agents thérapeutiques ou un véhicule pour de tels agents.

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