Fluorine-containing nitroazole derivatives and...

C - Chemistry – Metallurgy – 07 – D

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260/305, 167/47,

C07D 233/91 (2006.01) C07D 249/10 (2006.01) C07D 249/14 (2006.01) C07D 401/06 (2006.01)

Patent

CA 1329206

- 1- ABSTRACT A nitroazole derivative of the formula: NA-Rf (I) wherein NA is 3-nitro-1,2,4-triazol-1-yl and Rf is a fluorine-containing organic group provided that when NA is 2-nitroimdazol-1-yl, the fluorine-containing organic group has at least one fluorine atom on a carbon atom which bonds to the nitrogen atom of the imidazole ring or a carbon atom which bonds to said carbon atom. The nitroazole derivative of formula (I) is useful as a radiosensitizer.

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