C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/80 (2006.01) A61K 31/403 (2006.01) A61P 43/00 (2006.01) C07D 209/88 (2006.01)
Patent
CA 2471952
Fluoro substituted cycloalkanoindole derivatives of formula (1) and pharmaceutically acceptable salts thereof, wherein n is 0 or 1; m is 1, 3 or 3; R1 is H, C1-C3 alkyl, halogenated C1-C3 alkyl or cyclopropyl; R2 is 4-chlorophenyl or 2,4,6-trichlorophenyl are an-tagonists of prostaglandins, and as such are useful for the treatment of prostaglandin mediated diseases.
L'invention concerne des dérivés cycloalkanoindoles à substitution fluor qui constituent des antagonistes de la prostaglandine et qui peuvent donc être utilisés pour le traitement de maladies médiées par la prostaglandine.
Berthelette Carl
Lachance Nicolas
Li Lianhai
Sturino Claudio
Wang Zhaoyin
Gowling Lafleur Henderson Llp
Merck Frosst Canada & Co./merck Frosst Canada & Cie
Merck Frosst Canada Ltd.
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