C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
167/273, 260/603
C07C 33/42 (2006.01) A61K 31/135 (2006.01)
Patent
CA 1256453
ABSTRACT FLUOROALLYLAMINE DERIVATIVES Compounds of the following Formula I are novel inhibitors and some at least of said compounds selectively inhibit MAO-B: Image (I) wherein:- R1 and R2 independently represent hydrogen, chlorine or fluorine; R3 represents hydrogen or (C1-C4)alkyl; and X represents oxygen or sulfur. They are useful for the treatment of depression and, co-administered with L-dopa, in the treatment of Parkinsonism.
486625
Merrell Dow Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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