Fluorocarbon aerosol medicaments

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/56 (2006.01) A61K 9/12 (2006.01) A61K 9/72 (2006.01) A61K 31/138 (2006.01) A61P 11/00 (2006.01) B65D 83/14 (2006.01) A61M 11/00 (2006.01) A61M 15/00 (2006.01)

Patent

CA 2654849

A pharmaceutical aerosol formulation which comprises particulate medicament selected from the group consisting of salmeterol, fluticasone propionate and physiologically acceptable salts thereof and 1,1,1,2-tetrafluoroethane as propellant which formulation is substantially free of surfactant. There is also provided a canister suitable for delivering the pharmaceutical aerosol formulation which comprises a container capable of withstanding the vapour pressure of the propellant used, which container is closed with a metering valve and contains the pharmaceutical aerosol formulation. The formulation may be used for the treatment of respiratory disorders such as asthma. There is also provided use of an effective amount of a pharmaceutical aerosol formulation which is substantially free of surfactant and which comprises particulate medicament selected from the group consisting of salmeterol, fluticasone propionate and physiologically acceptable salts thereof and 1,1,1,2-tetrafluoroethane as propellant in the manufacture of a medicament for treating respiratory disorders, wherein the said medicament is administered by inhalation.

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