Fluorocarbon emulsions with reduced pulmonary gas-trapping...

Details Fluorocarbon emulsions with reduced pulmonary gas-trapping... Fluorocarbon emulsions with reduced pulmonary gas-trapping...

A - Human Necessities

61

K

A61K 31/02 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 35/14 (2006.01)

Patent

CA 2156922

A fluorocarbon emulsion which exhibits reduced pulmonary gas-trapping properties in species-sensitive laboratory animals is disclosed. Additionally, the fluorocarbon component(s) exhibit short organ retention time(s). The emulsion includes an aqueous phase, an emulsifier, and a fluorocarbon (or fluorocarbon composition), having a vapor pressure of less than about 8 torr to reduce pulmonary gas-trapping, and having an organ retention half life of less than about 6 weeks and more preferably less than about 3 to 4 weeks.

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