C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
150/14, 260/168.
C07D 498/08 (2006.01) C07D 498/18 (2006.01) G01N 33/84 (2006.01) G01N 33/86 (2006.01)
Patent
CA 1305133
ABSTRACT FLUOROGENIC AND CHROMOGENIC THREE-DIMENSIONAL IONOPHORES AS SELECTIVE REAGENTS FOR DETECTING IONS IN BIOLOGICAL FLUIDS Novel fluorogenic and chromogenic three-dimensional ionophores are provided which selectively bond ions such as potassium, sodium, and lithium, even in neutral aqueous or alcohol media. The novel ionophores comprise an "ion-recognizing system" fused to a "signal-moiety" through one or more heteroatoms having a non-bonded electron pair. The signal-moieties are selected from the group consisting of fused ring heterocyclics, fused aromatics, and subsituted aromatics having at least one nitro or azo moiety. The ion-recognizing system is a three-dimensional cryptand. The ionophores are ideal for the selective and direct termination of ions in biological or environmental samples and the like. 1405J
572609
Hammond George Simms
Lucas Mariann Elizabeth
Masilamani Divakaran
Allied-Signal Inc.
Gowling Lafleur Henderson Llp
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