Fluoromethylthioacetic acid compounds

Details Fluoromethylthioacetic acid compounds Fluoromethylthioacetic acid compounds

C - Chemistry, Metallurgy

07

D

260/492, 260/536

C07D 257/04 (2006.01) C07D 295/185 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1178609

- Abstract - An industrial intermediate useful e.g. for synthesizing organic solvents or medicinal or agricultural chemicals, the chemical name of which is monofluoromethylthioacetic acid (FCH2SCH2COOH) or difluoromethylthioacetic acid (F2CHSCH2COOH), or its carboxy derivative can be prepared e.g. by treating a thioglycolic acid ester with monofluoro- halomethane or difluorohalomethane in the presence of a base if required followed by a conventional modification of the produced ester e.g. to make an acid by hydrolysis, a salt by neutralization, a halide with a halogenating agent and from acid halide or anhydride an ester with an alcohol or an amide with an amine.

393292

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