Fluorosiloxane matrix controlled diffusion drug delivery system

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 77/24 (2006.01) A61K 47/34 (2006.01) A61K 47/48 (2006.01) C08G 77/20 (2006.01)

Patent

CA 2489987

Fluorinated side-chain siloxane copolymeric matrix controlled diffusion drug delivery systems are provided that allow controlled release of sustained concentrations of therapeutic agents within a treated area for a prolonged period of time. The favorable solubility characteristics of the fluorinated sidechains of the siloxane copolymeric matrix controlled diffusion drug delivery systems allow for manipulation of drug release rates depending on the particular therapeutic use and the particular needs of the patient.

La présente invention concerne des systèmes d'apport de médicament à diffusion régulée à matrice copolymère siloxane à chaînes latérales fluorées qui permettent de libérer de manière régulée des concentrations régulières d'agents thérapeutiques dans une région traitée sur une durée prolongée. Les caractéristiques de solubilité favorables des chaînes latérales fluorées des systèmes d'apport de médicament à diffusion régulée à matrice copolymère siloxane permettent de modifier les taux de libération du médicament en fonction de l'utilisation thérapeutique particulière et des besoins spécifiques du patient.

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