Fluticasone lotion having improved vasoconstrictor activity

A - Human Necessities – 61 – K

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A61K 31/57 (2006.01) A61K 8/63 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2347109

A fluticasone lotion having improved vasoconstrictor and anti-inflammatory activity and higher than expected potency. The fluticasone lotion contains 0.05 weight percent fluticasone propionate and an oil-in-water vehicle that includes excipients. The fluticasone lotion is unexpectedly efficacious while exhibiting an improved safety profile.

L'invention concerne une lotion de fluticasone présentant une action vasoconstrictrice et anti-inflammatoire améliorée, ainsi qu'une puissance dépassant toute attente. Cette lotion de fluticasone contient 0,05 pour cent en poids de propionate de fluticasone et un support huile dans eau renfermant des excipients. La lotion de fluticasone de cette invention se révèle particulièrement efficace et présente un profil d'innocuité amélioré.

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