C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 38/19 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) C07K 14/525 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01)
Patent
CA 2729351
Fusion proteins which act on the TWEAK and TRAIL signaling axes are provided. The proteins are useful in the treatment or amelioration of autoimmune diseases, particularly multiple sclerosis, as well as other diseases such as alloimmune diseases and cancer.
L'invention concerne des protéines de fusion qui agissent sur les axes de signalisation TWEAK et TRAIL. Les protéines sont utiles pour le traitement ou l'amélioration de maladies auto-immunes, notamment de la sclérose en plaques, ainsi que d'autres maladies telles que les maladies allo-immunes et le cancer.
Razmara Marjaneh
Tykocinski Mark L.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Of Pennsylvania
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