Foam-forming composition

Details Foam-forming composition Foam-forming composition

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 31/573 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2637408

The present invention relates to a novel foam-forming composition suitable for rectal administration of locally-acting pharmaceutically active ingredients, and the product adapted to administer said foam-forming composition. Also, the present invention relates to a method for its preparation. According to the present invention a foam-forming composition is provided which exhibits a high expansion ratio and at the same time conferring optimal appearance of the formed foam to allow sufficient contact time of the active to the target site in the intestine in order to obtain optimal local effect. The composition according to the present inventions provides superior properties for the treatment of rectal diseases.

La présente invention concerne une nouvelle composition moussante conçue pour l~administration par voie rectale d~agents pharmaceutiquement actifs à action locale. L~invention concerne également le produit destiné à administrer la composition moussante ainsi qu~un procédé pour la préparer. La composition moussante selon l~invention fait preuve d~un taux d~expansion élevé et confère en même temps un aspect optimal à la mousse formée permettant à l~agent actif d~être en contact avec le site cible dans l~intestin pendant une durée suffisante pour obtenir un effet local optimal. Ladite composition offre des qualités supérieures pour le traitement de maladies affectant le rectum.

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