C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) B01F 13/00 (2006.01) B01J 19/00 (2006.01) B01L 3/00 (2006.01) G01N 15/14 (2006.01) G01N 27/447 (2006.01)
Patent
CA 2373347
Methods and systems for particle focusing to increase assay throughput in microscale systems are provided. The invention includes methods for providing substantially uniform flow velocity to flowing particles in microfluidic devices. Methods of sorting members of particle populations, such as cells and various subcellular components are also provided. Integrated systems in which particles are focused and/or sorted are additionally included.
L'invention se rapporte à des procédés et à des systèmes de focalisation de particules qui permettent d'accroître le rendement d'analyses dans des systèmes de petite échelle. L'invention se rapporte à des procédés permettant d'assurer une vitesse d'écoulement sensiblement uniforme des particules en mouvement dans des dispositifs microfluidiques. L'invention se rapporte également à des procédés de tri des éléments de populations de particules, du type cellules et composants infracellulaires divers. L'invention se rapporte en outre à des systèmes intégrés dans lesquels les particules sont focalisées et/ou triées.
Alajoki Marja Liisa
Chow Andrea W.
Dubrow Robert S.
Kopf-Sill Anne R.
Parce J. Wallace
Caliper Life Sciences Inc.
Caliper Technologies Corporation
Fetherstonhaugh & Co.
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