Folate receptor binding conjugates of antifolates

Details Folate receptor binding conjugates of antifolates Folate receptor binding conjugates of antifolates

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2737496

Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.

L'invention concerne des conjugués d'antifolates, de lieurs libérables, et de médicaments, et des compositions pharmaceutiques les contenant. Les conjugués sont utiles pour traiter des maladies attribuables à des populations de cellules pathogènes. L'invention concerne également des procédés de traitement de ces maladies.

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