Folic acid derivatives and process for preparation

Details Folic acid derivatives and process for preparation Folic acid derivatives and process for preparation

C - Chemistry, Metallurgy

07

D

167/47, 260/242.

C07D 475/00 (2006.01) G01N 33/82 (2006.01)

Patent

CA 1150254

ABSTRACT Folic acid derivatives, such as radiolabeled pteroyltyrosine, are conveniently synthesized from either pteroic acid or by the direct condensation of 6-formylpterin with p-aminobenzoyltyrosine methyl ester. The radioiodinated derivatives are particularly useful in competitive protein binding and radioimmuno-assays of folate compounds.

349225

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