Follicular fluid for prolonged growth and survival of cells...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/00 (2006.01)

Patent

CA 2537149

The invention provides a method for preventing senescence and death of somatic cells by culturing the cells in the presence of serum and follicular fluid or components of follicular fluid. The somatic cells with a limited lifespan in vitro acquire properties of stem cells and can be passaged continuously, but only in the continuing presence of follicular fluid or components thereof.

L'invention concerne un procédé permettant de prévenir la sénescence et la mort de cellules somatiques, qui consiste à cultiver les cellules en présence de sérum et de fluide folliculaire ou de composants du fluide folliculaire. Les cellules somatiques à durée de vie limitée in vitro acquièrent des propriétés de cellules souches et peuvent être repiquées en continu, mais uniquement en présence continue du fluide folliculaire ou de ses composants.

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