Follistatin-related protein zfsta2

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2347968

The present invention relates to polynucleotide and polypeptide molecules for zfsta2, a novel member of the follistatin family. The polypeptides, and polynucleotides encoding them are useful for binding to members of the TGF- .beta. family and mediating central nervous system, reproductive, hematopoietic and bone-related activities. The present invention also includes antibodies to the zfsta2 polypeptides.

L'invention porte sur les molécules d'un polynucléotide et du polypeptide zfsta2 associé, nouveau membre de la famille des follistatines. Ledit polypeptide, et le polynucléotide codant pour lui permettent des fixations à des membres de la famille des TGF-.beta. et l'induction de certaines activités reproductrices, hématopoïétiques et d'ossification du SNC. L'invention porte également sur des anticorps anti-polypeptide zfsta2.

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