Fonctionalized complexand

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 9/96 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 49/06 (2006.01) A61K 49/08 (2006.01) A61K 51/04 (2006.01) A61K 51/10 (2006.01) C07D 257/00 (2006.01) C07D 257/02 (2006.01) C07F 1/08 (2006.01) C07F 5/00 (2006.01) C07F 7/24 (2006.01) C07K 16/00 (2006.01) C07K 17/02 (2006.01) G01N 33/533 (2006.01) G01N 33/60 (2006.01) A61K 43/00 (1990.01)

Patent

CA 2079206

2079206 9114458 PCTABS00007 The present invention relates to macrocyclic chelates and methods of use thereof. Specifically, the invention relates to a substituted 1,4,7,10-tetraazacyclododecane triacetic acid wherein the three triacetic acids are linked at three of the nitrogens of the macrocycle, and a hydrogen is attached to the fourth nitrogen of the macrocycle. The chelate exists as a mixture of the four possible structures (or isomers). The present invention also relates to the various uses of these particular chelating agents.

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