Food composition for prodromal dementia patients

Details Food composition for prodromal dementia patients Food composition for prodromal dementia patients

A - Human Necessities

23

L

A23L 1/29 (2006.01) A23L 1/30 (2006.01) A23L 1/304 (2006.01) A23L 1/305 (2006.01) A61K 31/14 (2006.01) A61K 31/202 (2006.01) A61K 31/7072 (2006.01)

Patent

CA 2704906

A composition comprising (a) one or more .omega.-3 fatty acids selected from DHA, DPA and EPA, (b) uridine or its equivalent, and (c) a methyl donor, useful in the treatment of a person having characteristics of a prodromal dementia patient. The characteristics include e.g. a level of more than 350 ng Total-tau per litre cerebrospinal fluid (CSF), and a weight ratio of abeta- 42/ Phospho-tau-181 of less than 6.5 in CSF.

La présente invention concerne une composition comprenant (a) au moins un acide gras ?-3 choisi parmi le DHA, le DPA et l'EPA, (b) de l'uridine ou équivalent et (c) un donneur de méthyle, utilisable dans le cadre du traitement d'une personne présentant des caractéristiques propres à un patient au stade prodromique de la démence. Ces caractéristiques comprennent, par exemple, un niveau supérieur à 350 ng de protéine tau totale par litre de liquide céphalo-rachidien et un rapport pondéral Abeta42/phospho-tau181 inférieur à 6,5 dans le liquide céphalo-rachidien.

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