C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) A01N 43/04 (2006.01) A61K 38/21 (2006.01) A61K 39/00 (2006.01) A61K 39/135 (2006.01) A61K 48/00 (2006.01) C07K 14/555 (2006.01) C12N 15/20 (2006.01) C12N 15/861 (2006.01)
Patent
CA 2445266
Early protection of susceptible animals against foot and mouth disease (FMD) may be achieved by inoculating the animals with a vaccine comprising an interferon DNA sequence. One day after inoculation, animals have been found protected from challenge with virulent foot and mouth disease virus. Co- administration with an effective foot and mouth disease virus vaccine provides protection prior to the development of specific immunity, a feature especially desireable during a FMD outbreak.
Il est possible de fournir une protection précoce à des animaux susceptibles de contracter la maladie de la fièvre aphteuse en les inoculant au moyen d'un vaccin comportant une séquence d'ADN d'interféron. Un jour après l'inoculation, ces animaux se sont révélés protégés lorsqu'ils ont été soumis à un test de provocation avec le virus virulent de la maladie de la fièvre aphteuse. L'administration simultanée de ladite séquence d'ADN et d'un vaccin efficace contre le virus de la maladie de la fièvre aphteuse permet de fournir une protection antérieurement au développement d'une immunité spécifique, ce qui est particulièrement souhaitable lors d'une éclosion de la maladie de la fièvre aphteuse.
Chinsangaram Jarasvech
Grubman Marvin J.
Koster Marla
Moraes Mauro P.
Borden Ladner Gervais Llp
The United States Of America As Represented By The Secretary Of Agricul Ture
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