Formation and resolution of dexibuprofen lysine

Details Formation and resolution of dexibuprofen lysine Formation and resolution of dexibuprofen lysine

C - Chemistry, Metallurgy

07

C

260/525.4, 260/5

C07C 51/41 (2006.01) C07C 51/487 (2006.01) C07C 57/30 (2006.01) C07C 227/34 (2006.01) C07C 229/26 (2006.01)

Patent

CA 2033871

044/MW25 18032 TITLE OF THE INVENTION: FORMATION AND RESOLUTION OF IBUPROFEN LYSINATE ABSTRACT OF THE DISCLOSURE A process is disclosed for the formation and resolution of (S)-ibuprofen-(S)-lysine. The process employs preferential crystallization to separate a pair of diasteromeric salts, (S)-ibuprofen-(S)-lysine and (R)-ibuprofen-(S)-lysine.

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