Formation of protein microparticles by antisolvent...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 1/30 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) C07K 14/62 (2006.01) C07K 14/695 (2006.01) C12N 9/00 (2006.01) C12N 9/08 (2006.01) C12N 9/98 (2006.01)

Patent

CA 2083027

Microparticles of a material are formed by bringing a supercritical antisolvent gas into contact with a solution of the material in a solvent at a controlled rate operable to expand the solution and precipitate the material. The small particulate material formed in accordance with the invention is particularly useful in the preparation of devices that provide control of the rate of drug release.

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