C - Chemistry – Metallurgy – 08 – J
Patent
C - Chemistry, Metallurgy
08
J
C08J 3/075 (2006.01) A61K 9/00 (2006.01) C05G 5/00 (2006.01) C08L 1/26 (2006.01) C08L 33/14 (2006.01)
Patent
CA 2638788
Hydrogels, and especially superporous hydrogels are dehydrated by subjecting them to lyophilization such that a water/hydrogel weight/weight ratio of from 0.005 to 0.1, thereby stabilizing them; the hydrogels may in particular, be produced using an ion--equilibration technique. Anionic polysaccharides are included in the hydrogel reaction mixture and cations are introduced either during or after hydrogel formation. Properties of the resulting hydrogel can be subsequently adjusted by treating the cation complexed gel with a different cation or cation mixture under equilibrating conditions. It has been found that by properly adjusting the cations and the sequence in which they are used in the equilibration process, superporous hydrogels can be formed that are highly absorbent while maintaining favorable structural properties, including strength, ruggedness, and resiliency. It has also been found that applying the dehydration conditions to them after their formation further stabilizes the hydrogels.
Gutierrez-Rocca Jose
Omidian Hossein
Kos Life Sciences Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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