Formation of triple helix complexes using a novel motif

Details Formation of triple helix complexes using a novel motif Formation of triple helix complexes using a novel motif

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2151263

Methods of recognizing, detecting and/or inhibiting or altering expression of a target sequence of nucleic acid by forming a triple helix complex using a novel motif. Triple helix complexes may be formed with either single stranded or double stranded target sequences. The stable triple helix complexes have been demonstrated to inhibit translation of an RNA target.

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